The OptMed Advantage
Methylidene malonate was extensively tested for biocompatibility and adhesive properties in topical and internal applications.
It has many advantages over current adhesives:
Customizable chemistry to facilitate optimization of adhesives to address specific unmet clinical needs
Adheres to wet and dry tissues
Achieves a strong bond while remaining very flexible and elastic
Generates minimal heat during polymerization
Main degradation by-products(1) via hydrolysis generate two safe byproducts, ethanol and glycolic acid.
(1) Breton P., Larras V., Roy D., Sagodira S., Limal D., Bonnafous D., Colin N., Bru N., Fattal E., Couvreur P., Biocompatible Poly(Methylidene Malonate) – Made Materials for Pharmaceutical and Biomedical Applications. European Journal of Pharmaceutics and Biopharmaceutics; Volume 68, Issue 3, March 2008, Pg 479-495
[1] BIOCOMPATIBLE POLY(METHYLIDENE MALONATE)-MADE MATERIALS FOR PHARMACEUTICAL AND BIOMEDICAL APPLICATIONS. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS; MARCH 2008